Idiopathic hypereosinophilic syndrome (IHES) is a leukoproliferative disorder with hypereosinophilia. The most common presentation is a cardiac manifestation, such as myocarditis. The pericardial effusion is a rare presentation of IHES, and it is even rarer for pericardial effusion and both pleural effusion to be expressed together.\nA 24-year-old male was admitted to our hospital with dyspnea, cough, and chest pain. Imaging studies showed bilateral pleural effusion and pericardial effusion. Effusion fluid analysis revealed elevated eosinophil count. His blood test also showed eosinophilia, and he didn\'t have any other diseases which cause eosinophilia. The histologic section of the pleura and pericardium showed eosinophilic infiltration in mesothelium. We diagnosed him with IHES with bilateral pleural and pericardial effusion together without cardiac involvement, which was a rare case among the IHES. We treated him with a high dose of steroid, and one month later, his eosinophilic count and chest X-ray returned to normal.
In this study, describes magnetic biocomposite as a biosorbent that use natural renewable resources and reduce adverse effects on the environment. The Pisum sativum peels powder and magnetite was encapsulated into alginate beads in aqueous calcium chloride solution to prepare a biocomposite material. Magnetic biosorption procedure of lead was optimized by Placket Burman Factorial Design. Biocomposite amount, pH, temperature and extraction time were evaluated as optimization parameters. In this work, biosorption yield of lead ions using magnetic biocomposite was calculated as 90±4% percent by Flame Atomic Absorption Spectrometry. Different sorption and thermodynamic parameters have been tested from sorption results by batch technique. The best-fitting isotherm is Freundlich model and theoretical capacity of biosorbent for lead ions was calculated as 74.05 mg/g. The report of biocomposite on the biosorption studies was presented.
Jian is a copper deposit located in the southwest corner of Sanandaj-Sirjan metamorphic belt in Iran. The greatest alterations of Jian occurred in the area are Chloritic and sericitic alterations affected on schist which along foliations the alteration is more intense. Hydrothermal alteration and sulphide mineralization developed in quartz-sericite-illite-kaolinite alteration zone with fine veining. The veinlets were accompanied by pervasive sericitization of feldspar mineral and its microliths groundmass. The sericite hydrothermal alteration is also characterized by feldspar destruction, mainly in association with sericite, chlorite and clay minerals. It is hypothesized that most of the copper mineralization was originally deposited as Bornite and chalcocite. Supergene oxidization of the orebody extends to a maximum depth of 20m. Isolated deep oxidation occurs along open fracture zones to depths of ~20 meters along vein filled fracture zones. Weak supergene copper enrichment occurs in a thin horizon (7to15-m thick) and argillic alteration with decrease of Na2O and MgO (6.16wt.%) By geochemical diagrams, it is revealed that Na2O, CaO, MnO, FeO, Al2O3, TiO2 and Fe2O3 reflect a reducing trend, K2O shows an increasing trend, P2O¬5 has a relatively fixed or constant trend. Trace elements such as Sr, Ni, and Cr have a reducing trend and Ba shows an increasing trend. The highest value of elements is as follows: Copper 30254 ppm, nickel 76ppm, and lead 848 ppm occurred in sericitic-argillic and chloritic alteration zones. Copper mineralization is directly related to quartz veining and wall rock alteration that developed with the host micaschists in the area.
Tree Species have the ability to change the amount of soil carbon sequestration, total nitrogen and other soil characteristics. In addition, pure and mixed planting cause changes in soil characteristics. Pine (Pinus nigra) and cedar (Cedrus libani) are fast-growing and specific Conifer species which are planted in different parts of the world. Thus, the main objective of this study is consideration of the effects of mentioned species on soil carbon sequestration (SCS), total nitrogen (TN) and some Soil Characteristics in 19-year-old pure and mixed Stands that afforested in Fandoghloo region, northwestern of Iran. Soil samples were taken from three different depths (0-15, 15-30 and 30-50 cm) and soil organic carbon (SOC), total N, available P, Ca, pH, EC, bulk density, base saturation and texture were measured. The results showed that carbon sequestration, total nitrogen and other physico- chemical Characteristics of soil in to the top 50 cm of soil were affected by pure and mixed afforested species. The highest amount of SCS was observed in 0-15 cm of cedrus libani pure Stand soil. Total means of SCS were 85.22, 85.74 and 90.34 (Mg ha-1) in cedrus libani, pinus nigra pure stands and mixed Pinus-cedrus stand, respectively. The highest amount of total nitrogen was obtained at a depth of 50-30 cm of soil in pure stand of pinus nigra .The total nitrogen were 6.20, 7.56 and 8.08( Mg ha-1 ) in pure cedrus libani, pinus nigra and mixed pinu nigras-cedrus libani stans, respectively. Overlay, the pure and mixed conifer stands had different impacts on soil characteristics, SCS, total N. There is the possibility that low acidity of soil in cedar pure stand comparison to the other causes an increase in the activity of microorganisms and more mixing of humus with soil. Correlation of SCS with SOC compound can also be the reason of this claim. The high concentration of nitrogen in the lower depths (30-50) in all three stands can occur because of leaching of this compound.
Peroxidase inhibition produced by phenolic compounds as hispidin and gallic acid, alkaloids as harmine and natural extracts of Inonotus hispidus and Marrubium vulgare were investigated in this study. No further studies have been found in this context. The results show that the phenolic and the alkaloidal extracts with the three molecules are potent inhibitors of horseradish peroxidase. Uric acid is used as a substrate reaction to find the enzymatic inhibition for the first time. The results show that the best inhibitor is hispidin with a value of IC50=23 µg/ml. Molecular docking has been carried out using AutoDock Vina program to discuss the nature of interactions and the mechanism of inhibition between both peroxidases (horseradish and thyroid) which is performed with and without heme group for the first time. However, the results show that all the docked molecules are competitive inhibitors confirming that no further studies have been published before. Thus, hispidin is more potent irreversible TPO inhibitor then propylthiouracil anti-thyroid drug. Its inhibition mechanism is well described through this work for the first time; which suggests is use as an anti-thyroid drug to treat hyperthyroidism.