The article deals with research of market capacity for organic products based on an analysis of consumer behavior across the Republic of Kazakhstan, with sociological survey serving as a basis. Recent years have seen the demand for organic products steadily growing both in the domestic and foreign markets. This makes it relevant and important to identify specific factors that will affect consumer behavior in the future, using the example of the local market. The purpose of the study is to determine the factors for promoting environmentally friendly products and to identify consumer demand patterns through social research tools.

The ability of a species to colonize new geographical areas is closely related to its morphological response to environmental gradients. Previous studies compared native and alien invasive species in their ability to modify their morphology in reaction to climatic and edaphic factors; however, taxonomically close species have been scarcely analyzed. In this study, morphological variability patterns associated with abiotic factors were evaluated in Trifolium polymorphum, a native species distributed from southern Brazil to northern Patagonia, and Trifolium repens, a species introduced as forage resource and naturalized in diverse environments of Southern South America. A morphometric study was carried out using herbarium specimens that were then georeferenced to obtain environmental and distributional data. Morphological traits along abiotic and geographical gradients were analyzed, predictive distribution and current and future niches were modelled. Our results showed that leaf morphology of T. repens responds to precipitation and temperature factors, which could explain its invasive behaviour in a wide range of environments. Morphological variability of the native T. polymorphum presented a low association with abiotic factors, suggesting possible difficulties in adapting to future environmental changes. Ecological niche modelling analysis showed several overlap areas between species in the current model and a greater expansion of the distribution range of the invasive species in future climate change scenarios.

Where the performance of a treatment is affected by the treatments applied to its neighboring units, neighbor balanced designs are used. These designs ensure that treatments comparisons will not be much affected by neighbor effects. Experimenters always prefer minimal designs but minimal neighbor designs can be constructed for v odd. For v even, minimal generalized neighbor designs (GNDs) are considered good alternate to the minimal neighbor designs. In this article, some generators are developed to obtain minimal circular GNDs in which 3v/2 unordered pairs of distinct treatments do not satisfy the neighbor balance property, where v is number of treatments. These designs are useful for experimentation in agriculture, horticulture and agroforestry.

A series of fluorinated 3,4-dihydro-2H-1,4-benzothiazine derivatives was synthesized starting from pentafluorobenzoic acid and 2-mercaptoethanol via aromatic nucleophilic substitution of fluorine atoms. They were characterized by spectral methods, X-ray diffraction analysis, and screened for the cardiotropic activity in vivo on mature male rats of line Wistar. The presence of a possible antiarrhythmic activity in the selected derivatives was tested, as was the effect on blood pressure in widely accepted models of arrhythmia. It was found that this series of chemical compounds has an antiarrhythmic effect and causes a monotonic increase in blood pressure within 3–5 min. As the most promising agents were selected 5,7-difluoro-3,4-dihydro-2H-benzo[1,4]thiazine-1,1-dioxide derivatives 3c and 5, containing a cyclopentylamine fragment at position 8.

The OC-AgNPs named after silver-nanoparticles obtained from the aqueous extract of Oxalis corniculata (OC), showed significant antiviral, anti-biofilm, and antibacterial activities against herpes simplex virus and six human isolates of multi-drug resistant (MDR) Staphylococcus aureus, Streptococcus pyogenes, Escherichia coli, Klebsiella pneumoniae, Salmonella typhi, and Pseudomonas aeruginosa. The formation of OC-AgNPs has been determined by the UV-Vis and FTIR spectroscopy; while particle morphology and distribution were determined by transmission electron microscopy (TEM). The cytotoxicity test of it was done by MTT assay on Vero cells; while its safety was assessed in triple-negative human breast cancer cell line MDA-MB-468. Plaque reduction test has been done for antiviral activity evaluation against HSV-1F. The anti-biofilm activity was evaluated by crystal violet assay followed by light and confocal microscopy; while the antibacterial activity by disk-diffusion and broth-dilution methods. The mechanism of anti-biofilm and antibacterial activity was examined by Field Emission Scanning Electron Microscopy (FESEM). The results exposed that biogenic OC-AgNP had a UV-Vis peak at 445 nm; particles average diameter of 40 nm with spherical morphology. The Cytotoxicity (CC50) of OC-AgNP in Vero cells was found to be 300µg/mL; while the survival percentage of MDA-MB-468 cells varied from 27.12 to 80.97% at 100 and 20 µM concentrations, respectively. The OC-AgNP posses moderate antiviral activity against HSV-1F at EC50 of 25µg/mL. The anti-biofilm activity was significant at 25-50 µg/mL against P. aeruginosa and E. coli; while the dose-dependent lowering of fluorescence intensity was found at 30-50 µM under both light and confocal microscope. The antibacterial activity was significant against P. aeruginosa (20 mm), K. pneumoniae (15 mm) E. coli (12 mm), S. typhi (10 mm), Streptococcus pyogenes (11 mm) and S. aureus (10 mm) with Minimum Inhibitory Concentration (MIC) of 0.65-0.90 µM (0.11 to 0.153 μg), respectively. Further, the FESE micrograph demonstrated the damage of membrane integrity and disruption of the membrane structure of P. aeruginosa at its MIC.

In the realm of human being thoughts of nature, Fourier analysis is considered as one of the greatest ideas that have been put forwarded by now. The Fourier transform shows any periodic functions can be rewritten as the sum of sinusoidal functions. Having Fourier transform view on real- world problem like gene DNA sequences, would make things intuitively simple to understand them than their initial formal domain view. In this study we used discrete Fourier transform (DFT) on gene\'s DNA sequences of set of genes governing milk production in bovine genome to develop a new gene clustering algorithm. The implementation of this algorithm is almost very handy and requires only simple routine mathematical operations. We sought, by transforming gene\'s DNA sequences configuration into frequency domain, it is possible to make some important features visible and hidden gene properties could be revealed. This is biologically appealing since via this transformation; no information is lost therefore we are not left with less degree of freedom. The results of different clustering methods were integrated using AdaBoost algorithms to come up with Insilco-like biological validation of our results. The results of clustering for proposed algorithm almost ended up with motivated results. We propose using some candidate genes sequences in accompany with other biologically unknown genes functions, most likely may assign some degree of relevant annotation in costless way to those genes using proposed algorithm here. We also, as a side, notice that there are so many empty rooms in current biological gene clustering investigation that DFT based methods would be quite helpful in shining in some biologically motivated lights.